Keywords exhibiting the greatest centrality and weight in this network (metastasis, tumor-infiltrating lymphocytes, immunotherapy, chemotherapy, PD-L1, nanoparticles, resistance, and subtypes) are expected to correspond to research niches within this theme, underscoring requirements pertaining to further TNBC-focused research concerning such niches, linked with avenues of investigation. The gene discussed is CD274; the disease is neoplasm.