IL6 and infection: Inflammation generated by infections is the primary cause of preterm labor, which causes higher levels of inflammatory cytokines. High concentrations of proinflammatory cytokines, such as interleukin-6 and interleukin-8 in serum, have been reported in women with symptoms of preterm labor and have been prospectively associated with preterm birth. Infection anywhere stimulates inflammatory response and many mediators, such as C-reactive protein (CRP) and alkaline phosphatase, are increased in serum [5-8].