Cardiac amyloidoses are grouped under three headings: AL amyloidosis due to amyloidogenic monoclonal light chain production of a plasma cell clone; hereditary TTR amyloidosis (ATTRv) caused by accumulation of mutated Transthyretin (TTR); and wild-type (non-hereditary) TTR amyloidosis (ATTRwt) (13). This evidence concerns the gene TTR and familial amyloid neuropathy.