CD22 and colorectal neoplasm: In accordance with the immune infiltration analysis, the average levels of basophils (CD22+) and eosinophils (CD45+) infiltration in colorectal tumors were significantly lower than those in normal colorectal tissues (P = 0.017 and P = 0.003, respectively), but the difference in T cell (CD3+) infiltration levels was not statistically significant (Fig. 5E).