TARDBP and neuroblastoma: To confirm and extend a previous finding that cytoplasmic TDP-43 co-aggregates with RACK1 in the neuroblastoma cell line SH-SY5Y [57], we transiently transfected HEK293T cells with HA-tagged wild-type (WT) TDP-43 or a nuclear localization signal (NLS)-deficient mutant of TDP-43, TDP-43ΔNLS.