The results showed that, compared with para-cancerous tissues, the expression of AGAP2-AS1 (t = 15.03, p < 0.001) and IGF2BP3 (t = 15.58, p < 0.001) increased significantly in ccRCC tissues (Fig. 1G). The gene discussed is AGAP2; the disease is nonpapillary renal cell carcinoma.