Their expressions were further verified in cell lines, which showed that compared with HK-2 cells, the levels of IGF2BP3 (p < 0.001) and AGAP2-AS1 (F = 48.38, p < 0.001) were significantly higher expressed in ccRCC cell lines of 786-O and ACHN (Fig. 1H). Here, AGAP2 is linked to nonpapillary renal cell carcinoma.