The targets identified include, RPS2 is a ribosomal protein that was reported to interact with MDM2 to control the levels of TP53/TRP53 [16], SIK1 serine/threonine kinase that regulates TP53 function in apoptosis triggered by lack of adhesion to suppress breast cancer metastasis [21]. This evidence concerns the gene SIK1 and breast carcinoma.