H19 and neoplasm: Tumor purity positively correlated with H19/ICR1 methylation β values (Pearson r = 0.43, p = 8.3e–08) and negatively correlated with KCNQ1OT1/ICR2 methylation β values (Pearson r = -0.46, p = 1.2e–08), which suggests that tumor purity was a confounding factor when determining the LOH/LOI status of 11p15.5 from the H19/ICR1 and KCNQ1OT1/ICR2 methylation β values.