This process resulted in a panel of HABP2 and CD163 with high performance for distinguishing HCC from LC (AUC: 0.935, sensitivity:0.838, specificity: 0.872) and from HC (AUC: 0.977, sensitivity:0.875, specificity: 0.907) (Supplementary Fig. 4a). Here, HABP2 is linked to hepatocellular carcinoma.