Powdered tetrandrine citrate (TetC), a novel highly water-soluble powdered cycloheximide salt, has strong anticancer activity not only in chronic myeloid leukemia, but also in breast cancer cells by inhibiting GPX4 expression and activation of NCOA4 to promote ferritinophagy in cancer cells inducing ferrogenic cell death [80]. This evidence concerns the gene NCOA4 and cancer.