Tyrosine kinase fusion papillary carcinoma, in particular NTRK and RET fusion carcinomas, are characterized by multilobulated/multinodular growth, intratumoral fibrosis, complex papillary architecture with glomerulid papillae and/or solid-trabecular growth, and prominent invasion of vascular spaces, particularly lymphatics. The gene discussed is RET; the disease is thyroid gland papillary carcinoma.