MAPT and Alzheimer disease: While our study employs the International Classification of Diseases, Tenth Revision (ICD-10) criteria for diagnosing dementia and MCI cases and relies on MRI for categorizing dementia into AD or VD, it’s important to note that current best practices emphasize the use of biomarkers such as amyloid and tau positivity in cerebrospinal fluid or amyloid PET scans for a more accurate diagnosis of AD.