Interestingly, previously accumulated evidence shows that FXS-associated neurobiological changes are brain region-specific (Anagnostou and Taylor, 2011; Varghese et al., 2017; Fetit et al., 2021) and hippocampus is among the brain regions that are affected by the loss of FMRP (Banker et al., 2021; Liu et al., 2022). Here, FMR1 is linked to fragile X syndrome.