In contrast to the results of the present study, in the study of Nikkhah‐Bodaghi et al., the administration of 2 g of N. sativa powder per day in 46 patients with ulcerative colitis for 6 weeks did not improve the serum levels of inflammatory and oxidative markers TNF‐α, hs‐CRP, and serum TAC, but it decreased the serum level of MDA (Nikkhah‐Bodaghi et al., 2019). This evidence concerns the gene TNF and ulcerative colitis.