Notably, CD44 is a commonly accepted marker of cancer stem cells (CSC) of different cancer entities including breast, colon, gastric, pancreas, glioma, ovarian (Zöller, 2011; Hu and Fu, 2012; Yan et al., 2015; Skandalis et al., 2019), and of epithelial to mesenchymal transition (EMT) a process vital for distant metastasis formation (Cho et al., 2012; Zhang et al., 2012; Jiang et al., 2015). The gene discussed is CD44; the disease is cancer.