Orlistat, a drug that inhibits gastric lipases and FAS, and triacsin C, an inhibitor of long-chain acyl CoA synthetase (ACS), both inhibit SARS-CoV-2 infection in VeroE6 cells when added 2h or 4h post-infection, but have minimal effect if cells are treated for 1h before infection, indicating a post-entry action. The gene discussed is LIPF; the disease is infection.