FASN-KO HEK293T-hACE2 cells are also resistant to virus infection, and eleven out of 22 FAS inhibitors blocked SARS-CoV-2-mNG infection, the most effective ones being TVB-3664, orlistat, TVB-2640, TVB-3166, GSK-214069, FASN-IN-4, and FT113. The gene discussed is FASN; the disease is viral infectious disease.