(27) sequenced circulating exosomal miRNAs from 5 patients with DM accompanied by interstitial lung disease and positive anti-MDA5 antibody, 5 patients with DM without myositis antibodies, and 5 healthy controls and found significant differences in has-miR-4488 and hsa-miR-1228-5p in all three comparisons. This evidence concerns the gene IFIH1 and interstitial lung disease.