(37) determined that miR-19b was downregulated while KLF13 was upregulated in peripheral blood mononuclear cells of patients with SLE and verified the binding and negative correlation between miR-19b and KLF13. They further discovered that umbilical cord blood-derived MSCs could enrich miR-19b in exosomes, resulting in the differentiation of CD4-positive T-cells into Tregs and reducing the production of inflammatory cytokines. Here, KLF13 is linked to systemic lupus erythematosus.