(37) Our results identified critical features of metastasis and tumor progression in hybrid cells, including genes and pathways involved in cell migration and invasion (TMSB10, AIF1, ARGHDIB, CAPG, RHOA, TYROBP, ACTB, S100A11), immune evasion (CD74, B2M, TNFAIP3), and altered metabolism (GPX1, SEPP1, UQCRB) (Fig. 3Cand Supplemental File 3). This evidence concerns the gene CD74 and neoplasm.