DHODH and glioblastoma: Indeed, the expression of the enzymes dihydroorotate dehydrogenase (DHODH) and 1‐orotate phosphoribosyl transferase and 2‐orotidine‐5′‐decarboxylase/uridine monophosphate synthetase, implicated in de novo biosynthesis of pyrimidines, is upregulated in GBM.