Furthermore, we observed downregulation of the expression of AP003774.2, DDX11-AS1, MIR924HG, MIR9-3HG, and AL451085.2 in HNSCC tissues compared to normal tissues, while ACTN1-AS1 and DOCK8-AS1 were upregulated. This evidence concerns the gene ACTN1 and head and neck squamous cell carcinoma.