A similar combination treatment of IP10–scFv fusion protein and dendritic cell–induced CD8+ cytotoxic T lymphocytes has been shown to recruit CXCR3+ CD8+ T cells, leading to cytotoxicity and apoptosis of glioma cells, thereby inhibiting glioma growth and prolonged survival [76] (Fig. 4) (Table 3). This evidence concerns the gene CD8A and central nervous system cancer.