In addition, some family members of SNHG can also regulate the drug resistance of NSCLC cells; for example, Wei et al. revealed that SNHG1 may reduce the cisplatin sensitivity of A549/DDP cells by increasing Rho-associated coiled-coil containing protein kinase 2 (ROCK2) expression by sponging and downregulating miR-101-3p [54]. The gene discussed is ROCK2; the disease is non-small cell lung carcinoma.