First, SNHG can directly act on downstream genes or signaling pathways to affect a series of biological behaviors of lung cancer cells; for example, Zhang et al. reported that SNHG1 may contribute to the migration and invasion of NSCLC cells by upregulating zinc finger E-box-binding homeobox 1 (ZEB1) [56]. This evidence concerns the gene SNHG1 and lung carcinoma.