Moreover, previous reports have indicated that arginine has the ability to directly activate the nutrient-sensing kinase, mammalian target of rapamycin complex 1 (mTORC1), and acts as an epigenetic regulator targeting TEAD4 to modulate oxidative phosphorylation (OXPHOS) in prostate cancer cells [17]. This evidence concerns the gene TEAD4 and Familial prostate cancer.