Abbreviations: SOFA-score: Sequential Organ Failure Assessment score, CRP: C-reactive protein, PCT: procalcitonin, IL-6: interleukin-6, GFR-CKD-EPI: Glomerular filtration rate - Chronic Kidney Disease Epidemiology Collaboration, AST: aspartate transaminase, ALT: alanine aminotransferase, LDH: lactate dehydrogenase, WBC: white blood cell, PLT: platelet, MPV: mean platelet volume, ACE2: Angiotensin-converting enzyme 2, n.d.: not determined. This evidence concerns the gene ACE2 and chronic kidney disease.