CRP and Sepsis: In the 90-day death group, the Lac content, white blood cell and neutrophil counts, CRP, PCT, IL-6, and d-dimer were all higher in the 90-day death group than in the survivor group (all p < 0.001), which was consistent with previous studies [19, 23] As a product of anaerobic metabolism, lactate is considered a powerful indicator for assessing the severity of sepsis [30].