ROBO1 and hypertensive disorder: Gene level association scores for ROBO1, calculated using the Multi-marker Analysis of GenoMic Annotation (MAGMA) algorithm [51] and Human Genetic Evidence (HuGE) score [52], available at the Cerebrovascular Disease Knowledge Portal [53], indicate a strong association of common and rare variants in ROBO1 with hypertension and diastolic and systolic BP.