For instance, reduced mRNA levels of KCNQ2 encoding the voltage-gated potassium channel Kv7.2, as well as mRNA levels of KCNA1 and KCNA2 encoding the voltage-gated potassium channels Kv1.1 and Kv1.2, respectively, were reported in spinal motor neurons of ALS patients [96]. Here, KCNA2 is linked to amyotrophic lateral sclerosis.