In subjects with iron deficiency with anaemia (IDA), a significant decrease in all iron parameters, iron conc., ferritin, transferrin saturation, TBIS, hepcidin serum levels, sTfR, along with lower Hgb % were estimated in the IDA group compared to those of control and ID groups respectively (P = 0.001). The gene discussed is TFRC; the disease is Iron deficiency anemia.