The data showed that hepcidin correlated positively with Hgb, AGP, hs-CRP, TAC, iron conc., ferritin, transferrin saturation (%), and negatively with TBIS, sTfR, and TOS as biomarkers of metabolic iron disorders in ID, IDA, and overloaded subjects, respectively. The gene discussed is ATP5MK; the disease is metabolic disease.