The findings indicated that 92 pathways were affected by the key targets of ACP (P < 0.05), mainly including pathways in cancer, hepatitis B, lipid and atherosclerosis, cell cycle, cellular senescence, human cytomegalovirus infection, PI3K-Akt signaling pathway, p53 signaling pathway, measles, kaposi sarcoma-associated herpesvirus infection, Epstein-Barr virus infection, and human T-cell leukemia virus 1 infection (Fig. 6A). Here, TP53 is linked to atherosclerosis.