AKT1 and cancer: The results of KEGG pathway enrichment showed that 185 pathways were affected by active components of ACP (P < 0.05), and the top 8 pathways (gene numbers ≥ 50) included metabolic pathways, pathways in cancer, lipid and atherosclerosis, PI3K-Akt signaling pathway, MAPK signaling pathway, chemical carcinogenesis-receptor activation, pathways of neurodegeneration-multiple diseases, and chemical carcinogenesis-reactive oxygen species (Fig. 3B).