Finally, we have conducted correlation analysis of the transcriptomic data of 368 cutaneous melanoma samples from patients and found a significant positive correlation of PD-L1 and IFN-γ (r = 0.737; p < 0.001), PD-L1 and STAT-1 (r = 0.778; p < 0.001), PD-L1 and IFN-γ driven CXCL10 (r = 0.721; p < 0.001), PD-L1 and the IFN-γ driven CXCL9 (r = 0.733; p < 0.001) and PD-L1 and acidosis driven MMP9 (r = 0.338; p < 0.001; Fig. S10). Here, MMP9 is linked to cutaneous melanoma.