In the univariable analysis, age, male sex, BMI, BVAS, FFS, dyslipidaemia, white blood cell count, haemoglobin, blood urea nitrogen, serum creatinine, serum total protein, serum albumin, CRP, and peripheral eosinophil count ≥ 175.0/mm3 were significantly associated with all-cause mortality in patients newly diagnosed with MPA and GPA. This evidence concerns the gene CRP and inherited lipid metabolism disorder.