In the multivariable analysis, male sex (HR 3.463, 95% confidence interval [CI] 1.561, 7.682), BVAS (HR 1.076, 95% CI 1.015, 1.141), FFS (HR 1.560, 95% CI 1.043, 2.332), dyslipidaemia (HR 3.349, 95% CI 1.497, 7.493), and serum albumin (HR 0.377, 95% CI 0.180, 0.789) were independently associated with all-cause mortality in patients newly diagnosed with MPA and GPA, whereas peripheral eosinophil count ≥ 175.0/mm3 was not (see Additional file 1). This evidence concerns the gene ALB and inherited lipid metabolism disorder.