To determine whether the expression of UBE2C was correlated with the clinicopathologic characteristics in cholangiocarcinoma patients (Table 2), we collected 182 cases of cholangiocarcinoma patients, 108 were male and 74 were female, of which 107 cholangiocarcinoma patients were < 65 years and 75 cholangiocarcinoma patients were male ≥ 65 years. This evidence concerns the gene UBE2C and cholangiocarcinoma.