UBE2C and cholangiocarcinoma: To understand the undisclosed functions of UBE2C in IHCC, we downloaded the top 200 differentially expressed genes presenting a positive relationship (Additional file 1: Table S1) or a negative relationship (Additional file 1: Table S2) to UBE2C from the cholangiocarcinoma data set (TCGA, Firehose Legacy, n = 51).