To compare myelination degree in mice with and without leukodystrophy, 9 MLC1 WT mice (median age, 17 months; age range, 12–20 months; 7 males) and 9 MLC1 KO mice (median age, 13 months; age range, 13–24 months; 6 females) were studies. Here, MLC1 is linked to leukodystrophy.