On the whole, VEGF concentrations were reported to rise postoperatively, with most pronounced serum levels at POD1 (1.79-fold after LS, 2.33-fold after OS) and POD4 (181-fold after LS and 2.29-fold after OS), although Kvarnström et al. [39, 40] stated decreasing values at 0–2 h after surgery (LS 65%, OS 95%). This evidence concerns the gene VEGFA and Leigh syndrome.