While a trend existed between expression and the estimated copy number of 5q genes (Pearson’s r = 0.35; Fig. S3), previously identified haploinsufficient candidates, such as CDC25C and CTNNA1, showed a limited to no drop of expression when compared to other AML (logFC = −0.06 and −0.8, respectively) or to CK AML (logFC = 0.1 and −0.6, respectively; Fig. 2A, Fig. S4A, B). This evidence concerns the gene CDC25C and acute myeloid leukemia.