The genes encoding for markers of inflammation, namely Tnf, Il1b, Il6, Il23a, and Cxcl10 were induced with infection in Tln1fl/fl mice and significantly decreased in the colon tissues from infected Tln1Δmye mice compared to infected Tln1fl/fl mice (Fig. 3A). The gene discussed is CXCL10; the disease is infection.