HSP90B1 and colorectal carcinoma: We discovered that RXC can downregulate the HSP90AA1 (RQ = 0.35) and HSP90B1 (RQ = 0.28) genes in CRC HCT116 cells by analyzing the transcripts of 82 target genes using a qPCR array, implying that disruption of these molecular chaperones could be a molecular target for RXC (Fig. 5A and Table S3).