GFAP and infection: Primary neuronal cultures from embryonic e17 mouse brains, infected with RML prions showed 5B2-positive long fibril-like PrPd aggregates at the cell periphery of GFAP-positive astrocytes with 6D11-positive PrPd puncta at perinuclear sites at three weeks post infection (Fig. 1H), thus corroborating the phenotypic features of the mAb pair in neuroblastoma cells.