Increased adherence to the SEAD has been associated with healthier gut microbiota7 and reduced levels of several cardiovascular risk factors, such as C-reactive protein, triglycerides, insulin, insulin resistance, pulse wave velocity, systolic blood pressure, total cholesterol, body mass index (BMI), and waist circumference.8–13 Reductions in the latter three risk factors have been reproduced in a randomized controlled trial.14 Finally, increased adherence to the SEAD has also been linked to decreased risk of myocardial infarction and all-cause mortality in older adults.4,15. The gene discussed is INS; the disease is myocardial infarction.