In breast cancer, high expression of CD4+ and CD8+ T cells (Lacko et al., 2008) and the accumulation oftumor-associated macrophages (Weinstein et al.,2013), dendritic cells (Szpor et al.,2021) and neutrophils (Wculek andMalanchi, 2015) were associated with prognosis, although there aredisagreements about whether they are related to favorable or unfavorable prognosis(Mahmoud et al., 2011; Stanton and Disis, 2016). This evidence concerns the gene CD8A and breast cancer.