We noted that a large proportion of genes specifically enriched within tumor-associated Treg cells compared with CD4+ Tconv cells (|FC| > 4, q < 0.05) under steady-state conditions were induced at high levels within CD4+ or CD8+ Tconv cells upon Treg cell ablation (Fig. 1C and 1D; Data file S1). Here, CD8A is linked to neoplasm.