Taken together with recent reports from our laboratory and others indicating roles for heterozygous mutations in CWH43 (20) and CFAP43 (14) in normal pressure hydrocephalus, our findings implicate heterozygous damaging mutations in a number of different genes that impair multiciliated ventricular cell function as potential contributors to adult-onset iNPH. This evidence concerns the gene CFAP43 and Hydrocephalus.