In addition, a large number of heat shock protein (HSP)-related genes (HSPA1A/B, HSP90AA1, HSPA6) were highly expressed in Basal-SCCIS-tumor cells, as well as activated keratin genes (KRT6A/B/C, KRT16, KRT17, KRT19) and S100 family genes (S100A7, S100A8, S100A9) (Figure 4G and H). Here, HSP90AA1 is linked to neoplasm.