Although AAV-Bambi monotherapy did suppress tumor growth, the combination of AAV-Bambi and IR (20 Gy, 1 dose) caused a more pronounced suppressive effect on tumor growth compared with that of mice treated with IR alone, assessed in terms of both tumor size (P = 0.0018) and animal survival (P = 0.0189) (Figure 4, B and C). The gene discussed is BAMBI; the disease is neoplasm.