We next evaluated how KSQ-001 responded to coculture with autologous tumor digests, with KSQ-001 maintaining the ability to produce IFN-γ in comparison with TILs, with cytokine release dependent upon MHC classes I and II, as inclusion of pooled antagonistic antibodies inhibited all IFN-γ production (Figure 6E). The gene discussed is HLA-C; the disease is neoplasm.