The boxplot (Figs. 2D and 2E) showed different mutation types in DLBCL patients, and Fig. 2F showed the top 10 genes with mutation frequency, including PIM1 (22%), IGLV3-1 (38%), IGLL5 (27%), IGHG1 (22%), IGHV2-70 (27%), BTG (27%), IGHM (24%), KMT2D (32%), IGLC2 (24%), CARD11 (22%). This evidence concerns the gene IGHM and diffuse large B-cell lymphoma.