Further studies showed that DP1 deficiency exacerbated inflammation in zymosan-induced peritonitis and myocardial infraction (Kong et al., 2016), bleomycin-induced acute lung injury (van den Brule et al., 2014), ulcerative colitis (Li et al., 2017), and angiogenesis (Murata et al., 2008) in mice. This evidence concerns the gene PTGDR and ulcerative colitis.