TLR7 and TLR8 recognize plasmodium‐derived RNA.[107]TLR8 has been associated with severe infected malaria in Mali children.[108]TLR9 (rs5743836) A > G appears to affect malaria progression and susceptibility in specific populations.[113, 114, 115] In Africa, the rs5743836 polymorphism is more common than in Europe. This evidence concerns the gene TLR7 and malaria.