Th1 responses play a critical role in TB immunity.[37] There are elevated CCR5 levels in Th cells in pulmonary TB patients.[37, 38]CCR5 expression is increased in individuals with active TB.[39, 40] In addition, CCR5 ligands are also increased during TB[38, 39, 40, 41] and cell‐mediated immunity (CMI) is a central determinant of TB resistance. This evidence concerns the gene CCR5 and pulmonary tuberculosis.