IFN‐γ was higher among individuals who were parasitemic than aparasitemic.[120] Reduced IFN‐α levels were associated with severe malaria in Kenyan and Gabonese children.[124, 125]IFN‐α regulates the immune response during human malarial infections.[124]IFN has differing effects on infectious diseases. This evidence concerns the gene IFNA1 and malaria.