CCR5 is expressed in macrophages and T cells acting as a co‐receptor for macrophage‐tropic viruses and plays an important role in SARS‐CoV‐2 infection.[45] The rs9845542 and rs12639314 variants of CCR5 were associated with severe COVID‐19 disease.[26]CCR5 plays a role in COVID‐19 severity.[46] The CCR5Δ32 deletion leads to reduced expression, playing a protective role against SARS‐CoV‐2 infection.[47, 48] This effect has also been observed in HIV.[46] This suggests that reduced expression of CCR5 is beneficial against TB, HIV, and COVID‐19. This evidence concerns the gene CCR5 and COVID-19.