IL6R and tuberculosis: In a study, M. tuberculosis‐infected macrophages secreted IL‐6 which overturned the responses of uninfected macrophages to interferon (IFN).[153] Elevated IL‐6 in the lungs and increased concentrations of IL‐1β correlated with TB progression.[41]IL‐6 was shown to positively and negatively contribute to host control against TB infection.[207] The reduced (interleukin 6 receptor) IL‐6R expression in TB was associated with decreased T helper cell 17 (Th17) response.