In plasma EV samples, the levels of NKX3-1 (FC = 5.42, p = 0.0003, AUC = 0.82) and miR-27a (FC = 1.61, p = 0.0129, AUC = 0.73) were significantly higher in PCa patients (Figures 3A,B). The gene discussed is NKX3-1; the disease is posterior cortical atrophy.