Comparison of NKX3-1 mRNA levels in RNAseq data from 502 prostate adenocarcinoma cases and 52 normal prostate tissues showed that its level in PCa tissues is substantially higher than in normal prostate tissues (Mann-Whitney test, p = 6.65 × 10−5) (Figure 6A). Here, NKX3-1 is linked to posterior cortical atrophy.