CDK1 and leukemia: Inhibition of CDK1 due to the phosphorylation of the kinase on Tyr15 residue by flavonoids (Casagrande and Darbon, 2001) as well as induction of G2/M phase arrest and apoptosis by the flavonoid tamarixetin on human leukemia cells (Nicolini et al., 2014) have previously been reported.